Article
A study of the association of (Val66Met) polymorphism in the brain-derived neurotrophic factor gene with alcohol dependence and extreme violence in Chinese males.
Neuroscience letters - 24 Jun 2005
Tsai Shih-Jen, Liao Ding-Lieh, Yu Younger W-Y, Chen Tai-Jui, Wu Hung-Chi, Lin Chun-Hui, Cheng Chih-Ya, Hong Chen-Jee
Abstract excerpt
From studies of genetic-knockout animals, brain-derived neurotrophic factor (BDNF), a member of the neurotrophin growth-factor family, has been implicated in both alcohol preference and aggressive behaviour. To test whether a BDNF genetic variant may be associated with alcohol-dependent and violent behaviours, we studied Val66Met polymorphism of the BDNF-gene in 110 cases of alcohol-dependence, in 134 extremely...
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