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Article

Altered regulation of the OmpF porin by Fis in Escherichia coli during an evolution experiment and between B and K-12 strains.

Journal of bacteriology - 1 Jan 2011

Crozat Estelle, Hindré Thomas, Kühn Lauriane, Garin Jérome, Lenski Richard E, Schneider Dominique

Abstract excerpt

The phenotypic plasticity of global regulatory networks provides bacteria with rapid acclimation to a wide range of environmental conditions, while genetic changes in those networks provide additional flexibility as bacteria evolve across long time scales. We previously identified mutations in the global regulator-encoding gene fis that enhanced organismal fitness during a long-term evolution experiment with...

Topics

Base Sequence
Electrophoresis, Gel, Two-Dimensional
Escherichia coli
Escherichia coli Proteins
Factor For Inversion Stimulation Protein
Gene Deletion
Gene Expression Regulation
Molecular Sequence Data
Mutation
Porins

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PMID: 21097626
DOI: 10.1128/JB.01341-10
PMCID: PMC3019833

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