Article
Surface light chain phenotype in indolent lymphomas: lack of prognostic significance.
American journal of hematology - 1 May 1990
VanderMolen L A, Duffey P L, Cossman J, Jaffe E S, Longo D L
Abstract excerpt
The indolent follicular and diffuse lymphomas are neoplasms of B-cell origin. In several other B-cell neoplastic disorders, including multiple myeloma, hairy cell leukemia, and chronic lymphocytic leukemia, the light chain isotype of the surface immunoglobulin has been reported to have prognostic significance. Patients with tumors expressing lambda light chains usually fare more poorly than those with kappa light...
Topics
- Humans
- Immunoglobulin Light Chains
- Immunohistochemistry
- Lymphoma
- Phenotype
- Prognosis
- Receptors, Antigen, B-Cell