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Article

Immunophenotypic, cytogenetic, and mutational features of chronic lymphocytic leukemia/small lymphocytic lymphoma with atypical immunophenotype.

Cytometry. Part B, Clinical cytometry - 1 May 2026

Wang Wei J, Wang Sa A, Fang Hong, Wei Qing, Jorgensen Jeffrey L, Hu Shimin, Xu Jie, Li Shaoying, Tang Guilin, Tang Zhenya, Medeiros L Jeffrey, Wang Wei

Abstract excerpt

Flow cytometric analysis plays an important role in the diagnosis of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). Most CLL cases show a typical immunophenotype characterized by the expression of CD5, CD23, CD43, ROR1, and CD200, along with dim expression of B-cell markers. However, some show an atypical immunophenotype. The immunophenotypic, cytogenetic, and mutational profiles of atypical...

Topics

Humans
Leukemia, Lymphocytic, Chronic, B-Cell
Immunophenotyping
Mutation
Flow Cytometry
Female
Aged
Male
Middle Aged
Trisomy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Aged, 80 and over

Receptor Tyrosine Kinase-like Orphan Receptors

Antigens, CD20

Chromosomes, Human, Pair 12

Antigens, CD

Source

Identifiers

PMID: 40814768
DOI: 10.1002/cyto.b.22248

Genes

ROR1
CD5
CD200
CD22
KMT2D
KRAS
NRAS
SMARCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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