A screening methodology based on Random Forests to improve the detection of gene-gene interactions.

Abstract excerpt

The search for susceptibility loci in gene-gene interactions imposes a methodological and computational challenge for statisticians because of the large dimensionality inherent to the modelling of gene-gene interactions or epistasis. In an era in which genome-wide scans have become relatively common, new powerful methods are required to handle the huge amount of feasible gene-gene interactions and to weed out...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Asthma