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Article

Cloning, sequencing, expression, and site-directed mutagenesis of the gene from Clostridium perfringens encoding pyruvoyl-dependent histidine decarboxylase.

Biochemistry - 9 Jan 1990

van Poelje P D, Snell E E

Abstract excerpt

The DNA encoding pyruvoyl-dependent histidine decarboxylase (HisDCase) of Clostridium perfringens was cloned, sequenced, and overexpressed in Escherichia coli. The gene encodes a single polypeptide of 320 amino acids, Mr 35,526, demonstrating that clostridial HisDCase, which has an (alpha beta)6...

Topics

Alanine
Amino Acid Sequence
Base Sequence
Binding Sites
Carboxy-Lyases
Cloning, Molecular
Clostridium perfringens
Enzyme Precursors
Escherichia coli
Histidine Decarboxylase
Lactobacillus
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Recombinant Proteins

Sequence Homology, Nucleic Acid

Serine

Source

Identifiers

PMID: 2108713
DOI: 10.1021/bi00453a016

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2108713-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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