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Article

Structures of the N47A and E109Q mutant proteins of pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii.

Acta crystallographica. Section D, Biological crystallography - 1 Apr 2008

Soriano Erika V, McCloskey Diane E, Kinsland Cynthia, Pegg Anthony E, Ealick Steven E

Abstract excerpt

Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) catalyzes the first step of the polyamine-biosynthetic pathway in plants and some archaebacteria. The pyruvoyl group of PvlArgDC is generated by an internal autoserinolysis reaction at an absolutely conserved serine residue in the proenzyme, resulting in two polypeptide chains. Based on the native structure of PvlArgDC from Methanococcus jannaschii, the...

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PMID: 18391404
DOI: 10.1107/S0907444908000474
PMCID: PMC2467525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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