Article
A systematic strategy for large-scale analysis of genotype phenotype correlations: identification of candidate genes involved in African trypanosomiasis.
Nucleic acids research - 1 Jan 2007
Fisher Paul, Hedeler Cornelia, Wolstencroft Katherine, Hulme Helen, Noyes Harry, Kemp Stephen, Stevens Robert, Brass Andrew
Abstract excerpt
It is increasingly common to combine Microarray and Quantitative Trait Loci data to aid the search for candidate genes responsible for phenotypic variation. Workflows provide a means of systematically processing these large datasets and also represent a framework for the re-use and the explicit declaration of experimental methods. In this article, we highlight the issues facing the manual analysis of microarray...
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