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Article

Papillary thyroid carcinoma shows elevated levels of 2-hydroxyglutarate.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2011

Rakheja Dinesh, Boriack Richard L, Mitui Midori, Khokhar Shama, Holt Shelby A, Kapur Payal

Abstract excerpt

Elevated levels of D: -2-hydroxyglutarate (D: -2-HG) occur in gliomas and myeloid leukemias associated with mutations of IDH1 and IDH2. L: -2-Hydroxyglutaric aciduria, an inherited metabolic disorder, predisposes to brain tumors. Therefore, we asked whether sporadic cancers, without IDH1 or IDH2...

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Source

Identifiers

PMID: 21080253
DOI: 10.1007/s13277-010-0125-6

Genes

IDH1
IDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21080253-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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