Article
Ancestral informative marker selection and population structure visualization using sparse Laplacian eigenfunctions.
PloS one - 4 Nov 2010
Zhang Jun
Abstract excerpt
Identification of a small panel of population structure informative markers can reduce genotyping cost and is useful in various applications, such as ancestry inference in association mapping, forensics and evolutionary theory in population genetics. Traditional methods to ascertain ancestral informative markers usually require the prior knowledge of individual ancestry and have difficulty for admixed...
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