Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cervimycin C resistance in Bacillus subtilis is due to a promoter up-mutation and increased mRNA stability of the constitutive ABC-transporter gene bmrA.

FEMS microbiology letters - 1 Dec 2010

Krügel Hans, Licht Andreas, Biedermann Gesine, Petzold Andreas, Lassak Jürgen, Hupfer Yvonne, Schlott Bernhard, Hertweck Christian, Platzer Matthias, Brantl Sabine, Saluz Hans-Peter

Abstract excerpt

Two independent cervimycin C (CmC)-resistant clones of Bacillus subtilis were identified, each carrying two mutations in the intergenic region preceding the ABC transporter gene bmrA. In the double mutant, real-time PCR revealed an increased amount of bmrA mRNA with increased stability. According...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anthracyclines
Share to Artificial Gene Fusion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP-Binding Cassette Transporters

Share to Bacillus subtilis

Share to Drug Resistance, Bacterial

Share to Electrophoretic Mobility Shift Assay

Share to Genes, Reporter

Share to RNA Stability

Source

Identifiers

PMID: 21077936
DOI: 10.1111/j.1574-6968.2010.02143.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21077936-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cervimycin C resistance in Bacillus subtilis is due to a promoter up-mutation and increased mRNA stability of the constitutive ABC-transporter gene bmrA.PMID 21077936Read ↗

Increased stability of bmr3 mRNA results in a multidrug-resistant phenotype in Bacillus subtilis.Semantic proximity Read ↗

The multidrug efflux transporter of Bacillus subtilis is a structural and functional homolog of the Staphylococcus NorA proteinSemantic proximity Read ↗

Structural and functional characterization of the Bacillus megaterium uvrBA locus and generation of UV-sensitive mutants.Semantic proximity Read ↗

Activation of Antibiotic Production in Bacillus spp. by Cumulative Drug Resistance Mutations.Semantic proximity Read ↗

A pmrA constitutive mutant sensitizes Escherichia coli to deoxycholic acid.Semantic proximity Read ↗

Acquired bacitracin resistance in Enterococcus faecalis is mediated by an ABC transporter and a novel regulatory protein, BcrR.Semantic proximity Read ↗

Zwittermicin A resistance gene from Bacillus cereus.Semantic proximity Read ↗

Identification and characterization of a novel multidrug resistance operon, mdtRP (yusOP), of Bacillus subtilis.Semantic proximity Read ↗

Characterization of a two-gene operon epeRA involved in multidrug resistance in Streptomyces clavuligerus.Semantic proximity Read ↗

Characterisation of a natural variant of the γ-butyrolactone signalling receptor.Semantic proximity Read ↗

The expression of recombinant genes in Escherichia coli can be strongly stimulated at the transcript production level by mutating the DNA-region corresponding to the 5'-untranslated part of mRNA.Semantic proximity Read ↗

Molecular analysis of BcrR, a membrane-bound bacitracin sensor and DNA-binding protein from Enterococcus faecalis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.