Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A pmrA constitutive mutant sensitizes Escherichia coli to deoxycholic acid.

Journal of bacteriology - 1 Feb 2006

Froelich Jamie M, Tran Khoa, Wall Daniel

Abstract excerpt

An Escherichia coli mutant was isolated and shown to be polymyxin B resistant. Mapping and sequence analysis revealed a missense mutation at codon 53 within the pmrA (basR) gene that results in a G-to-V substitution. Fusions of promoters from the pmrC, yibD, and pmrH genes with the lacZ reporter...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Drug Resistance, Bacterial
Share to Escherichia coli

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

Share to Lipid A

Share to Mutation

Share to Polymyxin B

Source

Open in PubMed Open full text

Identifiers

PMID: 16428424
DOI: 10.1128/JB.188.3.1180-1183.2006
PMCID: PMC1347340

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16428424-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A pmrA constitutive mutant sensitizes Escherichia coli to deoxycholic acid.PMID 16428424Read ↗

CrrB Positively Regulates High-Level Polymyxin Resistance and Virulence in Klebsiella pneumoniaeSemantic proximity Read ↗

Identification and genetic characterization of PmrA-regulated genes and genes involved in polymyxin B resistance in Salmonella enterica serovar typhimurium.Semantic proximity Read ↗

Regulation of polymyxin resistance and adaptation to low-Mg2+ environments.Semantic proximity Read ↗

PmrD is required for modifications to escherichia coli endotoxin that promote antimicrobial resistance.Semantic proximity Read ↗

Identification of the lipopolysaccharide modifications controlled by the Salmonella PmrA/PmrB system mediating resistance to Fe(III) and Al(III).Semantic proximity Read ↗

Identification and functional analysis of Salmonella enterica serovar Typhimurium PmrA-regulated genes.Semantic proximity Read ↗

Cervimycin C resistance in Bacillus subtilis is due to a promoter up-mutation and increased mRNA stability of the constitutive ABC-transporter gene bmrA.Semantic proximity Read ↗

pmrA(Con) confers pmrHFIJKL-dependent EGTA and polymyxin resistance on msbB Salmonella by decorating lipid A with phosphoethanolamine.Semantic proximity Read ↗

Multidrug resistant phenotype of Bacillus subtilis spontaneous mutants isolated in the presence of puromycin and lincomycin.Semantic proximity Read ↗

Evidence for efflux pumps, other than PmrA, associated with fluoroquinolone resistance in Streptococcus pneumoniae.Semantic proximity Read ↗

The periplasmic murein peptide-binding protein MppA is a negative regulator of multiple antibiotic resistance in Escherichia coli.Semantic proximity Read ↗

Nucleotide sequence of the Escherichia coli regulatory gene mprA and construction and characterization of mprA-deficient mutants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.