Article
Increased stability of bmr3 mRNA results in a multidrug-resistant phenotype in Bacillus subtilis.
Journal of bacteriology - 1 Nov 2004
Ohki Reiko, Tateno Kozue
Abstract excerpt
A spontaneous mutant isolated in the presence of a high concentration of puromycin acquired a multidrug-resistant phenotype. Expression of the bmr3 gene was dramatically increased. A base substitution, T to A at the +4 position, detected in the mutant resulted in the stabilization of bmr3 mRNA.
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