Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Coinheritance of α-thalassemia decreases the risk of cerebrovascular disease in a cohort of children with sickle cell anemia.

Hemoglobin - 1 Jan 2010

Belisário André Rolim, Rodrigues Cibele Velloso, Martins Marina Lobato, Silva Célia Maria, Viana Marcos Borato

Abstract excerpt

The study estimated α-thalassemia (α-thal) prevalence and assessed its associations with clinical and hematological features in a random sample of Brazilian children with sickle cell anemia (208 Hb SS and 13 Hb S-β⁰-thal). α-Thalassemia genotyping was carried out by multiplex polymerase chain reaction (m-PCR) for seven alleles. Clinical and hematological data were retrieved from the 221 children's medical files....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Globins
Share to alpha-Thalassemia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Analysis of Variance

Share to Anemia, Sickle Cell

Share to Brazil

Share to Cerebrovascular Disorders

Share to Hemoglobin, Sickle

Share to Risk Assessment

Source

Identifiers

PMID: 21077759
DOI: 10.3109/03630269.2010.526003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Coinheritance of α-thalassemia decreases the risk of cerebrovascular disease in a cohort of children with sickle cell anemia.PMID 21077759Read ↗

Genetic polymorphisms and cerebrovascular disease in children with sickle cell anemia from Rio de Janeiro, Brazil.Semantic proximity Read ↗

Influence of the βs haplotype and α-thalassemia on stroke development in a Brazilian population with sickle cell anaemia.Semantic proximity Read ↗

Association of alpha-thalassemia, TNF-alpha (-308G>A) and VCAM-1 (c.1238G>C) gene polymorphisms with cerebrovascular disease in a newborn cohort of 411 children with sickle cell anemia.Semantic proximity Read ↗

Alpha thalassemia, but not βS-globin haplotypes, influence sickle cell anemia clinical outcome in a large, single-center Brazilian cohort.Semantic proximity Read ↗

Alpha-thalassemia protects against cerebrovascular disease in children with sickle cell anemia.Semantic proximity Read ↗

Co-Inheritance of α-thalassemia gene mutation in patients with sickle cell Disease: Impact on clinical and hematological variables.Semantic proximity Read ↗

Reticulocyte count is the most important predictor of acute cerebral ischemia and high-risk transcranial Doppler in a newborn cohort of 395 children with sickle cell anemia.Semantic proximity Read ↗

Co-Inheritance of alpha-thalassemia and sickle cell disease in a cohort of Angolan pediatric patients.Semantic proximity Read ↗

Common α-globin variants modify hematologic and other clinical phenotypes in sickle cell trait and disease.Semantic proximity Read ↗

Frequencies and phenotypic consequences of association of α- and β-thalassemia alleles with sickle-cell disease in Bahrain.Semantic proximity Read ↗

Potential Association of Sickle Cell Disease Genotypes (Ss, as, Sβ Thalassemia) With Abo Blood Groups: In Indian PopulationSemantic proximity Read ↗

Molecular characteristics of pediatric patients with sickle cell anemia and stroke.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.