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Article

Co-Inheritance of α-thalassemia gene mutation in patients with sickle cell Disease: Impact on clinical and hematological variables.

Nigerian journal of clinical practice - 1 Jun 2021

Ali Al-Barazanchi Z A, Abdulateef S S, Hassan Meaad Kadhum

Abstract excerpt

BACKGROUND: Sickle cell disease (SCD) is a monogenic, phenotypically highly variable disease with multisystem pathology. The phenotypic heterogeneity of SCD is attributed to environmental and genetic factors such as fetal hemoglobin and co-inheritance of α-thalassemia. OBJECTIVES: To look for different types of α-thalassemia gene mutations among SCD patients and evaluate the influence of the co-inheritance of...

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Identifiers

PMID: 34121736
DOI: 10.4103/njcp.njcp_11_20

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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