Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Study on suitability of KOD DNA polymerase for enzymatic production of artificial nucleic acids using base/sugar modified nucleoside triphosphates.

Molecules (Basel, Switzerland) - 12 Nov 2010

Kuwahara Masayasu, Takano Yuuki, Kasahara Yuuya, Nara Hiroki, Ozaki Hiroaki, Sawai Hiroaki, Sugiyama Akio, Obika Satoshi

Abstract excerpt

Recently, KOD and its related DNA polymerases have been used for preparing various modified nucleic acids, including not only base-modified nucleic acids, but also sugar-modified ones, such as bridged/locked nucleic acid (BNA/LNA) which would be promising candidates for nucleic acid drugs. Howeve...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA-Directed DNA Polymerase
Share to Molecular Structure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Nucleic Acids

Share to Nucleotides

Share to Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 21076389
DOI: 10.3390/molecules15118229
PMCID: PMC6259326

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21076389-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Study on suitability of KOD DNA polymerase for enzymatic production of artificial nucleic acids using base/sugar modified nucleoside triphosphates.PMID 21076389Read ↗

DNA Polymerase Variants with High Processivity and Accuracy for Encoding and Decoding Locked Nucleic Acid Sequences.Semantic proximity Read ↗

5-methylcytosine-sensitive variants of Thermococcus kodakaraensis DNA polymerase.Semantic proximity Read ↗

Variety of Nucleotide Polymerase Mutants Aiming to Synthesize Modified RNA.Semantic proximity Read ↗

Long and accurate PCR with a mixture of KOD DNA polymerase and its exonuclease deficient mutant enzyme.Semantic proximity Read ↗

The Effect of γ Phosphate Modified Deoxynucleotide Substrates on PCR Activity and Fidelity.Semantic proximity Read ↗

[Nucleic acid syntheses and molecular recognition].Semantic proximity Read ↗

Functional Comparison of Laboratory-Evolved XNA Polymerases for Synthetic Biology.Semantic proximity Read ↗

Structural Studies of HNA Substrate Specificity in Mutants of an Archaeal DNA Polymerase Obtained by Directed Evolution.Semantic proximity Read ↗

DNA polymerase-catalyzed incorporation of nucleotides modified with a G-quadruplex-derived DNAzyme.Semantic proximity Read ↗

Expanding the repertoire of DNA polymerase substrates: template-instructed incorporation of non-nucleoside triphosphate analogues by DNA polymerases beta and lambda.Semantic proximity Read ↗

Thermostable DNA polymerase from Thermus thermophilus B35: preparation and study of a modified form of the enzyme with high affinity to ddNTP.Semantic proximity Read ↗

Crystal structure of d(gcGXGAgc) with X=G: a mutation at X is possible to occur in a base-intercalated duplex for multiplex formation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.