Article
Coincident idiopathic focal segmental glomerulosclerosis collapsing variant and diabetic nephropathy in an African American homozygous for MYH9 risk variants.
Human pathology - 1 Feb 2011
Gopalakrishnan Isai, Iskandar Samy S, Daeihagh Pirouz, Divers Jasmin, Langefeld Carl D, Bowden Donald W, Hicks Pamela J, Rocco Michael V, Freedman Barry I
Abstract excerpt
Familial clustering of disparate kidney diseases including clinically diagnosed hypertensive and diabetic nephropathy, idiopathic focal segmental glomerulosclerosis, and HIV-associated nephropathy are often observed in African Americans. Admixture mapping recently identified the nonmuscle myosin heavy chain 9 gene (MYH9) as a susceptibility factor strongly associated with several nondiabetic etiologies of...
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