Article
Mutations affecting two adjacent amino acid residues in the alpha subunit of RNA polymerase block transcriptional activation by the bacteriophage P2 Ogr protein.
Journal of bacteriology - 1 Dec 1994
Ayers D J, Sunshine M G, Six E W, Christie G E
Abstract excerpt
The bacteriophage P2 ogr gene product is a positive regulator of transcription from P2 late promoters. The ogr gene was originally defined by compensatory mutations that overcame the block to P2 growth imposed by a host mutation, rpoA109, in the gene encoding the alpha subunit of RNA polymerase....
Topics
- Alleles
- Base Sequence
- Chromosome Mapping
- Chromosomes, Bacterial
- DNA-Directed RNA Polymerases
- Enterobacteriaceae
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Genes, Reporter
- Molecular Sequence Data
- Mutation
- Peptide Fragments
- Promoter Regions, Genetic
- Salmonella typhimurium