Article
Modulation of chondrocyte phenotype for tissue engineering by designing the biologic-polymer carrier interface.
Biomacromolecules - 1 Nov 2006
Mahmood Tahir A, Miot Sylvie, Frank Oliver, Martin Ivan, Riesle Jens, Langer Robert, van Blitterswijk Clemens A
Abstract excerpt
Therapeutic strategies based on cell and tissue engineering can be advanced by developing material substrates that effectively interrogate the biological compartment, with or without the complimentary local release of growth factors. Poly(ether ester) segmented copolymers were engineered as model material systems to elucidate the interfacial molecular events that govern the function of adhered cells. Surface...
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