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Article

TLR5 as an anti-inflammatory target and modifier gene in cystic fibrosis.

Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 2010

Blohmke Christoph J, Park Julie, Hirschfeld Aaron F, Victor Rachel E, Schneiderman Julia, Stefanowicz Dorota, Chilvers Mark A, Durie Peter R, Corey Mary, Zielenski Julian, Dorfman Ruslan, Sandford Andrew J, Daley Denise, Turvey Stuart E

Abstract excerpt

New treatments are needed to improve the health of people with cystic fibrosis (CF). Reducing lung-damaging inflammation is likely to be beneficial, but specific anti-inflammatory targets have not been identified. By combining cellular immunology with a population-based genetic modifier study, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21068401
DOI: 10.4049/jimmunol.1001513

Genes

TLR5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21068401-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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