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Article

PI3Kinase signaling in glioblastoma.

Journal of neuro-oncology - 1 Jul 2011

Lino M M, Merlo A

Abstract excerpt

Glioblastoma (GBM) is the most common primary tumor of the CNS in the adult. It is characterized by exponential growth and diffuse invasiveness. Among many different genetic alterations in GBM, e.g., mutations of PTEN, EGFR, p16/p19 and p53 and their impact on aberrant signaling have been thoroughly characterized. A major barrier to develop a common therapeutic strategy is founded on the fact that each tumor has...

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Source

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Identifiers

PMID: 21063898
DOI: 10.1007/s11060-010-0442-z
PMCID: PMC3116122

Genes

EGFR
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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