Article
THE EFFECT OF ISLET CELL CULTURE IN VITRO AT 24°C ON GRAFT SURVIVAL AND MHC ANTIGEN EXPRESSION
1 Feb 1990
Abstract excerpt
A period of in vitro culture prior to transplantation has been shown to prolong the survival of many types of MHC-incompatible endocrine grafts. The effectiveness of this strategy has been attributed to a selective depletion of intragraft antigen-presenting cells. We report that in vitro culture at 24 degrees C results in a significantly better survival of rat isolated islet allografts than does culture at 37...
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