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Article

The structure and repertoire of small interfering RNAs in Leishmania (Viannia) braziliensis reveal diversification in the trypanosomatid RNAi pathway.

Molecular microbiology - 1 Feb 2013

Atayde Vanessa D, Shi Huafang, Franklin Joseph B, Carriero Nicholas, Notton Timothy, Lye Lon-Fye, Owens Katherine, Beverley Stephen M, Tschudi Christian, Ullu Elisabetta

Abstract excerpt

Among trypanosomatid protozoa the mechanism of RNA interference (RNAi) has been investigated in Trypanosoma brucei and to a lesser extent in Leishmania braziliensis. Although these two parasitic organisms belong to the same family, they are evolutionarily distantly related raising questions about the conservation of the RNAi pathway. Here we carried out an in-depth analysis of small interfering RNAs (siRNAs)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23217017
DOI: 10.1111/mmi.12117
PMCID: PMC3556230

Genes

AGO1

Provenance

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