Article
Interpretation of genotypic resistance to predict darunavir/ritonavir failure in antiretroviral experienced patients.
Journal of acquired immune deficiency syndromes (1999) - 1 Feb 2012
Sterrantino Gaetana, Zaccarelli Mauro, Trotta Michele, De Luca Andrea, Borghi Vanni, Meraviglia Paola, Corsi Paola, Bonora Stefano, Leoncini Francesco, Zazzi Maurizio
Abstract excerpt
From the Italian Antiretroviral Resistance Cohort Analysis database, 1104 patients starting ritonavir-boosted darunavir-containing regimen were included as follows: 118 subsequently failed treatment at a median of 11 months (interquartile range: 5-20); 3 years failure proportion: 24.6%. HIV Drug Resistance Database and ANRS interpretation algorithms were associated with a progressive risk prediction of...
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