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Article

SPLUNC1 regulation in airway epithelial cells: role of toll-like receptor 2 signaling

5 Nov 2010

Abstract excerpt

BACKGROUND: Respiratory infections including Mycoplasma pneumoniae (Mp) contribute to various chronic lung diseases. We have shown that mouse short palate, lung, and nasal epithelium clone 1 (SPLUNC1) protein was able to inhibit Mp growth. Further, airway epithelial cells increased SPLUNC1 expression upon Mp infection. However, the mechanisms underlying SPLUNC1 regulation remain unknown. In the current study, we...

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PMID: 21054862
DOI: 10.1186/1465-9921-11-155

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