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Article

Functional roles of SPLUNC1 in the innate immune response against Gram-negative bacteria

20 Jul 2011

Abstract excerpt

PLUNC (palate, lung and nasal epithelium clone)-associated gene originally referred to one gene, but now has been extended to represent a gene family that consists of a number of genes with peptide sequence homologies and predicted structural similarities. PLUNC-like proteins display sequence homology with BPI (bactericidal/permeability-increasing protein), a 456-residue cationic protein produced by precursors of...

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PMID: 21787346
DOI: 10.1042/bst0391051

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