Article
Isolation of a Bacillus subtilis mutant defective in constitutive O6-alkylguanine-DNA alkyltransferase.
Mutation research - 1 Jan 1990
Morohoshi F, Munakata N
Abstract excerpt
A mutant of Bacillus subtilis defective in the constitutive activity of O6-alkylguanine-DNA alkyltransferase was isolated from a strain (ada-1) deficient in the adaptive response to DNA alkylation. Cells carrying the mutation dat-1 which was responsible for the defect in constitutive activity exh...
Topics
- Alkyl and Aryl Transferases
- Alkylating Agents
- Bacillus subtilis
- Cell Survival
- DNA Repair
- Electrophoresis, Polyacrylamide Gel
- Genes, Bacterial
- Methyltransferases
- Mutagens
- Mutation
- O(6)-Methylguanine-DNA Methyltransferase
- Transferases
