Article
The 5352 A allele of the pro-inflammatory caspase-1 gene predicts late-acquired stent malapposition in STEMI patients treated with sirolimus stents.
Heart and vessels - 1 May 2011
Bergheanu Sandrin C, Pons Douwe, van der Hoeven Bas L, Liem Su-San, Siegerink Bob, Schalij Martin J, van der Bom Johanna G, Jukema J Wouter
Abstract excerpt
Late-acquired stent malapposition (LASM) is a common finding after sirolimus-eluting stent (SES) implantation and may be the cause for late stent thrombosis. Inflammation may play a pivotal role in LASM just as it plays in stent restenosis. We have therefore investigated seven polymorphisms involved in inflammatory processes, related in previous reports to restenosis, on the risk of LASM in SES patients. Patients...
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