Article
The interleukin 1B-511 polymorphism is associated with the risk of developing restenosis after coronary stenting in Mexican patients.
Human immunology - 1 Feb 2008
Miranda-Malpica Emma, Martínez-Rios Marco Antonio, Fragoso José Manuel, Delgadillo-Rodríguez Hilda, Rodríguez-Pérez José Manuel, González-Quesada Carlos, Martínez-Rodríguez Nancy, Saldaña-Mendoza Arturo, Peña-Duque Marco Antonio, Vargas-Alarcón Gilberto
Abstract excerpt
Inflammation is the primary response to vessel wall injury caused by stent placement in coronary arteries. Cytokines of the interleukin-1 family are central regulators in immunoinflammatory mechanisms. The objective of this study was to test for association between IL-1 family gene polymorphisms and risk for restenosis after coronary stent placement. The IL-1B-511, IL-1F10.3, RN.4T>C, RN.6/1C>T, RN.6/2C>G, and...
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