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Article

Modulation of fate determinants Olig2 and Pax6 in resident glia evokes spiking neuroblasts in a model of mild brain ischemia.

Stroke - 1 Dec 2010

Kronenberg Golo, Gertz Karen, Cheung Giselle, Buffo Annalisa, Kettenmann Helmut, Götz Magdalena, Endres Matthias

Abstract excerpt

BACKGROUND AND PURPOSE: Although in vitro studies suggest that non-neurogenic regions of the adult central nervous system potentially contain multipotent parenchymal progenitors, neurons are clearly not replaced in most brain regions after injury. Here, in a well-established model of mild transient brain ischemia, we explored Olig2 antagonism and Pax6 overexpression as potential avenues to redirect endogenous...

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Identifiers

PMID: 21051674
DOI: 10.1161/STROKEAHA.110.583039

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DCX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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