Article
In vivo fate analysis reveals the multipotent and self-renewal features of embryonic AspM expressing cells.
PloS one - 29 Apr 2011
Marinaro Cinzia, Butti Erica, Bergamaschi Andrea, Papale Alessandro, Furlan Roberto, Comi Giancarlo, Martino Gianvito, Muzio Luca
Abstract excerpt
Radial Glia (RG) cells constitute the major population of neural progenitors of the mouse developing brain. These cells are located in the ventricular zone (VZ) of the cerebral cortex and during neurogenesis they support the generation of cortical neurons. Later on, during brain maturation, RG cells give raise to glial cells and supply the adult mouse brain of Neural Stem Cells (NSC). Here we used a novel...
Topics
- Alleles
- Animals
- Calmodulin-Binding Proteins
- Cell Culture Techniques
- Cell Lineage
- Cell Proliferation
- Cerebral Cortex
- Embryonic Stem Cells
- Green Fluorescent Proteins
- Mice
- Mice, Transgenic