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Article

An increased risk of differentiated thyroid carcinoma in Iran with the 677C→T homozygous polymorphism in the MTHFR Gene.

Cancer epidemiology - 1 Feb 2011

Fard-Esfahani Pezhman, Fard-Esfahani Armaghan, Saidi Parinaz, Fayaz Shima, Mohabati Reyhaneh, Majdi Mina

Abstract excerpt

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) involves in folic acid metabolism which influences DNA methylation. A single nucleotide polymorphism (SNP) called 677C→T in MTHFR gene causes producing a thermolabile enzyme with reducing function and eventually defects DNA methylation. To d...

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Source

Identifiers

PMID: 21050834
DOI: 10.1016/j.canep.2010.10.001

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21050834-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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