Article
Decrease in gastric cancer susceptibility by MTHFR C677T polymorphism in Ardabil Province, Iran.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 1 Jan 2013
Hosseini-Asl S Saied, Pourfarzi Farhad, Barzegar Abazar, Mazani Mohammad, Farahmand Nima, Niasti Elham, Yazdanbod Abbas, Didevar Reza, Akhavan Homa, Malekzadeh Reza
Abstract excerpt
BACKGROUND/AIMS: Gastric cancer, as the fourth most frequent malignancy worldwide, has the highest rate among cancer-related disorders in Ardabil province, located in North-West Iran. Methylene tetrahydrofolate reductase is one of the cancer susceptibility genes with considerable polymorphisms. Methylene tetrahydrofolate reductase C677T leads to a decrease of about 30% in its product activity and is reported to...
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