The role of Ile3434Thr XRCC7 gene polymorphism in differentiated thyroid cancer risk in an Iranian population.

doi:10.6091/ibj.1078.2012

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Article

The role of Ile3434Thr XRCC7 gene polymorphism in differentiated thyroid cancer risk in an Iranian population.

Iranian biomedical journal - 1 Jan 2012

Rahimi Maryam, Fayaz Shima, Fard-Esfahani Armaghan, Modarressi Mohammad Hossein, Akrami Seyed Mohammad, Fard-Esfahani Pezhman

Abstract excerpt

BACKGROUND: The aim of this study was to understand any association between differentiated thyroid carcinoma (DTC) and Ile3434Thr XRCC7 gene polymorphism (GenBank accession number: rs7830743). DTC is the most prevalent thyroid neoplasm, which includes papillary and follicular cell carcinoma. XRCC7 gene encodes a protein that functions in non-homologous end joining DNA repair pathway. Non-synonymous polymorphisms...

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PMID: 23183621
DOI: 10.6091/ibj.1078.2012
PMCID: PMC3600962

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