Comparative evaluation of seven resistance interpretation algorithms and their derived genotypic inhibitory quotients for the prediction of 48 week virological response to darunavir-based salvage regimens.

doi:10.1093/jac/dkq384

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Article

Comparative evaluation of seven resistance interpretation algorithms and their derived genotypic inhibitory quotients for the prediction of 48 week virological response to darunavir-based salvage regimens.

The Journal of antimicrobial chemotherapy - 1 Jan 2011

Gonzalez de Requena Daniel, Bonora Stefano, Viganò Ottavia, Calcagno Andrea, Cometto Cristina, D'Avolio Antonio, Baietto Lorena, Ghisetti Valeria, Magnani Silvia, Ferramosca Stefania, Vitiello Paola, Galli Massimo, Rusconi Stefano, Di Perri Giovanni

Abstract excerpt

BACKGROUND: the darunavir genotypic inhibitory quotient (gIQ) has been suggested as one of the predictors of virological response to darunavir-containing salvage regimens. Nevertheless, which resistance algorithm should be used to optimize the calculation of gIQ is still debated. The aim of our study was to compare seven different free-access resistance algorithms and their derived gIQs as predictors of 48 week...

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PMID: 21037251
DOI: 10.1093/jac/dkq384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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