Article
Effect of iodine on early stage thyroid autonomy.
Genomics - 1 Feb 2011
Müller Kathrin, Krohn Knut, Eszlinger Markus, Ludgate Marian, Führer Dagmar
Abstract excerpt
Thyroid autonomy is a frequent cause of thyrotoxicosis in regions with iodine deficiency. Epidemiological data suggest that iodide may influence the course of pre-existing thyroid autonomy. Making use of FRTL-5 cells stably expressing a constitutively activating TSH receptor mutation as an in vitro model of thyroid autonomy, we investigated the impact of iodide on proliferation, function and changes in global...
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