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Article

Expression of iodine metabolism genes in human thyroid tissues: evidence for age and BRAFV600E mutation dependency.

Clinical endocrinology - 1 Apr 2009

Espadinha Carla, Santos Jorge Rosa, Sobrinho Luís G, Bugalho Maria João

Abstract excerpt

CONTEXT: Children present a higher susceptibility to developing thyroid cancer after radioiodine exposure and also a higher frequency of functional metastases than adults. OBJECTIVE: To assess the mRNA expression of the sodium/iodide (Na(+)/I(-)) symporter (NIS), the Pendred syndrome gene (PDS), thyroperoxidase (TPO), thyroglobulin (Tg) and TSH receptor (TSH-R) in normal thyroid tissues (NTTs) and papillary...

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Topics

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Share to Iodide Peroxidase
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptors, Thyrotropin

Share to Sulfate Transporters

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Share to Thyroglobulin

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Source

Identifiers

PMID: 18710471
DOI: 10.1111/j.1365-2265.2008.03376.x

Genes

TPO
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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