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Article

Interaction between two distinct plaque-cloned human immunodeficiency viruses (HIVs): the possible existence of heterozygous virus.

Microbiology and immunology - 1 Jan 1990

Masuda T, Harada S

Abstract excerpt

To know the biological significance of the HIV variation, we investigated the interaction between two different HIV clones. Two distinct clones were mixed and propagated by infecting MT-4 cells. After passaging the mixture viruses 8 times, and cloning by the plaque method, we obtained not only viruses of homogeneous type like each parental clone but also heterogeneous-type viruses which showed a mixture of two...

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PMID: 2098634
DOI: 10.1111/j.1348-0421.1990.tb01527.x

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