Interaction between two distinct plaque-cloned human immunodeficiency viruses (HIVs): the possible existence of heterozygous virus.

doi:10.1111/j.1348-0421.1990.tb01527.x

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Article

Interaction between two distinct plaque-cloned human immunodeficiency viruses (HIVs): the possible existence of heterozygous virus.

Microbiology and immunology - 1 Jan 1990

Masuda T, Harada S

Abstract excerpt

To know the biological significance of the HIV variation, we investigated the interaction between two different HIV clones. Two distinct clones were mixed and propagated by infecting MT-4 cells. After passaging the mixture viruses 8 times, and cloning by the plaque method, we obtained not only vi...

Topics

Animals
Blotting, Southern
Cells, Cultured
Cloning, Molecular
DNA, Viral
Genetic Variation
Genotype
HIV-1
Phenotype
Proviruses
Restriction Mapping
Viral Plaque Assay

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