Article
Phenotypic mixing between human immunodeficiency virus and vesicular stomatitis virus or herpes simplex virus.
Journal of acquired immune deficiency syndromes - 1 Jan 1990
Zhu Z H, Chen S S, Huang A S
Abstract excerpt
Superinfection of H9 cells persistently infected with human immunodeficiency virus (HIV) with thermolabile vesicular stomatitis virus (VSV) or herpes simplex virus (HSV) led to the synthesis of hybrid progeny. These phenotypic mixtures were able to infect HeLa or Chinese hamster ovary cell lines, leading to the production of HIV p24 antigen and infectious HIV. This production was abrogated by prior incubation of...
Topics
- Animals
- Antigens, Viral
- Cell Line
- Gene Products, gag
- HIV Antigens
- HIV Core Protein p24
- HIV-1
- HeLa Cells
- Humans
- Phenotype
- Simplexvirus
- Vesicular stomatitis Indiana virus
