Article
Mutagenicity of 11 cigarette smoke condensates in two versions of the mouse lymphoma assay.
Mutagenesis - 1 Mar 2011
Guo Xiaoqing, Verkler Tracie L, Chen Ying, Richter Patricia A, Polzin Gregory M, Moore Martha M, Mei Nan
Abstract excerpt
Cigarette smoke condensate (CSC) is genotoxic in nearly all assays in which it has been tested. In this study, we investigated the mutagenicity of 11 CSCs using the microwell and soft-agar versions of the mouse lymphoma assay (MLA). These CSCs were prepared from commercial or experimental cigarettes, 10 of them were produced using International Organisation for Standardisation (ISO) conditions and one CSC was...
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