Article
ERCC1 expression by immunohistochemistry and EGFR mutations in resected non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Jun 2008
Lee Kyung-Hun, Min Hye Sook, Han Sae-Won, Oh Do-Youn, Lee Se-Hoon, Kim Dong-Wan, Im Seock-Ah, Chung Doo Hyun, Kim Young Tae, Kim Tae-You, Heo Dae Seog, Bang Yung-Jue, Sung Sook Whan, Kim Joo Hyun
Abstract excerpt
Expression of excision repair cross-complementation group 1 (ERCC1) is important for resistance to platinum agents. Mutations of epidermal growth factor receptor (EGFR) are related to the responsiveness to tyrosine kinase inhibitors in non-small cell lung cancer (NSCLC). This study was performed to determine if ERCC1 expression and EGFR are related to the prognosis of resected NSCLC, and to determine if ERCC1...
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