Article
Treatment of non-small-cell lung cancer and pharmacogenomics: where we are and where we are going.
Current opinion in oncology - 1 Mar 2006
Rosell Rafael, Cuello Mauricio, Cecere Fabiana, Santarpia Mariacarmela, Reguart Noemi, Felip Enriqueta, Taron Miquel
Abstract excerpt
PURPOSE OF REVIEW: This review highlights the numerous molecular biology findings in the field of lung cancer with potential therapeutic impact in both the near and distant future. RECENT FINDINGS: Abundant preclinical and clinical data indicate that BRCA1 mRNA expression is a differential modulator of chemotherapy sensitivity. Single nucleotide polymorphisms in the excision repair cross-complementing 1 gene...
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