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Article

CSN5/Jab1 controls multiple events in the mammalian cell cycle.

FEBS letters - 19 Nov 2010

Yoshida Akihiro, Yoneda-Kato Noriko, Panattoni Martina, Pardi Ruggero, Kato Jun-ya

Abstract excerpt

The COP9 signalosome (CSN) complex is critical for mammalian cell proliferation and survival, but it is not known how the CSN affects the cell cycle. In this study, MEFs lacking CSN5/Jab1 were generated using a CRE-flox system. MEFs ceased to proliferate upon elimination of CSN5/Jab1. Rescue expe...

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Identifiers

PMID: 20974137
DOI: 10.1016/j.febslet.2010.10.039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20974137-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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