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Virus Population Homogenization following Acute Human Immunodeficiency Virus Type 1 Infection

1 Nov 2002

Abstract excerpt

Understanding the properties of human immunodeficiency virus type 1 (HIV-1) variants capable of establishing infection is critical to the development of a vaccine against AIDS. Previous studies of men have shown that the HIV-1 env gene is homogeneous early in infection, leading to the suggestion that infection is established by a single transmitted variant. However, we report here that all of eight homosexual men...

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PMID: 12414937
DOI: 10.1128/jvi.76.23.11953-11959.2002

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