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Article

Mutant p53 subverts p63 control over KLF4 expression in keratinocytes.

Oncogene - 24 Feb 2011

Cordani N, Pozzi S, Martynova E, Fanoni D, Borrelli S, Alotto D, Castagnoli C, Berti E, Viganò M A, Mantovani R

Abstract excerpt

Genetic experiments established that p63 is crucial for the development and maintenance of pluri-stratified epithelia and KLF4 for the barrier function of the skin. KLF4 is one of the factors that reprogram differentiated cells to iPS. We investigated the relationship between p63 and KLF4 using RNA interference, overexpression, chromatin immunoprecipitation and transient transfections with reporter constructs. We...

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Share to Chromatin Immunoprecipitation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Keratinocytes

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Source

Identifiers

PMID: 20972454
DOI: 10.1038/onc.2010.474

Genes

KLF4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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