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Article

Functional and structural evaluation of cysteine residues in the human arsenic (+3 oxidation state) methyltransferase (hAS3MT).

Biochimie - 1 Feb 2011

Song Xiaoli, Geng Zhirong, Li Xiangli, Zhao Qun, Hu Xin, Zhang Xinrong, Wang Zhilin

Abstract excerpt

Arsenic (+3 oxidation state) methyltransferase (AS3MT) catalyzes the methylation of inorganic arsenic (iAs) and plays important role in the detoxication of this metalloid. There are fourteen cysteine residues in the human AS3MT (hAS3MT), among which twelve are absolutely conserved; Cys334 and Cys360 are unique; Cys368 and Cys369 are identified as a CysCys pair. The roles of several conserved cysteine residues in...

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Identifiers

PMID: 20971157
DOI: 10.1016/j.biochi.2010.10.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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