Article
Arsenic (+3 oxidation state) methyltransferase and the inorganic arsenic methylation phenotype.
Toxicology and applied pharmacology - 15 Apr 2005
Li Jiaxin, Waters Stephen B, Drobna Zuzana, Devesa Vicenta, Styblo Miroslav, Thomas David J
Abstract excerpt
Inorganic arsenic is enzymatically methylated; hence, its ingestion results in exposure to the parent compound and various methylated arsenicals. Both experimental and epidemiological evidences suggest that some of the adverse health effects associated with chronic exposure to inorganic arsenic may be mediated by these methylated metabolites. If iAs methylation is an activation process, then the phenotype for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
