Article
Sustained delayed gastric emptying during repeated restraint stress in oxytocin knockout mice.
Journal of neuroendocrinology - 1 Nov 2010
Babygirija R, Zheng J, Bülbül M, Cerjak D, Ludwig K, Takahashi T
Abstract excerpt
We have recently shown that impaired gastric motility observed in acute restraint stress was restored following repeated restraint stress in mice. Repeated restraint stress up-regulates oxytocin mRNA expression and down-regulates corticotrophin-releasing factor (CRF) mRNA expression at the hypothalamus. Oxytocin knockout mice (OXT-KO) have been widely used to study the central oxytocin signalling pathways in...
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