Article
Stress and arousal: the corticotrophin-releasing factor/hypocretin circuitry.
Molecular neurobiology - 1 Dec 2005
Winsky-Sommerer Raphaëlle, Boutrel Benjamin, de Lecea Luis
Abstract excerpt
The hypocretins (also know as orexins) are two neuropeptides now commonly described as critical components for maintaining and regulating the stability of arousal. Several lines of evidence have raised the hypothesis that hypocretin-producing neurons are part of the circuitries that mediate the hypothalamic response to acute stress. New data indicate that the corticotrophin-releasing factor (CRF) peptidergic...
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