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Article

A conditional knockout mouse line of the oxytocin receptor.

Endocrinology - 1 Jul 2008

Lee Heon-Jin, Caldwell Heather K, Macbeth Abbe H, Tolu Selen G, Young W Scott

Abstract excerpt

Oxytocin plays important roles in reproductive physiology and various behaviors, including maternal behavior and social memory. Its receptor (Oxtr) is present in peripheral tissues and brain, so a conditional knockout (KO, -/-) would be useful to allow elimination of the receptor in specific sites at defined times. We created a line of mice in which loxP sites flank Oxtr coding sequence (floxed) enable Cre...

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Identifiers

PMID: 18356275
DOI: 10.1210/en.2007-1710
PMCID: PMC2453083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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